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Pectins in general can serve as prebiotics.45 Deglycyrrhizinated licorice root (400mg): Licorice without glycyrrhizin, a compound that can lead to serious side effects such as headache, fatigue, high blood pressure, and heart attack

For CNS-targeted research specifically, topical delivery remains largely impractical because the compound must still reach the brain after crossing the skina double barrier problem

heterogeneity in study design, dosage, preparation, and small sample sizes limits definitive conclusions

Providing supplemental glycine theoretically supports this adaptation

Exscientia introduced DSP-1181 for obsessive-compulsive disorder (OCD) using AI to accelerate compound screening and preclinical optimization